Paris
Banned in some countries, promoted in others — the drug hydroxychloroquine as a potential treatment for the new coronavirus is dividing opinion worldwide.
Scientists looking to find licenced medicines that could be repurposed as a treatment for COVID-19 had started tests of hydroxychloroquine, normally used to treat arthritis, and chloroquine, an anti-malarial. Both drugs can produce potentially serious side effects, particularly heart arrhythmia, leading many experts to warn against their use outside of clinical trials.
But that has not stopped prominent figures like US President Donald Trump endorsing hydroxychloroquine despite a lack of evidence of its efficacy. Escalating the debate, The Lancet on May 22 published a study of nearly 100,000 coronavirus patients that showed no benefit in treating them with the two drugs – and even increased the likelihood of them dying in hospital.
This led the World Health Organization to suspend clinical trials of hydroxychloroquine, but dozens of scientists have since raised concerns over the study’s methodology. The Lancet corrected part of the data, but researchers have stood by their conclusions. Countries worldwide vary on their own policies.
The study prompts several countries to halt the use of hydroxychloroquine. France does so on May 27, days after controversial French doctor Didier Raoult – whose own methodology has been questioned – rejected the study and stood by his belief the drug can help patients recover from the virus.
Other countries including Italy, Egypt, Tunisia, Colombia, Chile, El Salvador, Cape Verde, Albania, and Bosnia and Herzegovina also ban the use of the drug for COVID-19 patients, though in Italy it remains possible in clinical trials.—APP
