‘Insufficient evidence’ that weight loss supplements work


RESEARCHERS have recently presented the results of the first global analysis in 19 years of clinical trials for weight loss supplements.

Drawing on two literature reviews, they found insufficient evidence to warrant the recommendation of supplements for weight loss.

The study’s authors drew their conclusions from 121 clinical trials involving nearly 10,000 participants.

According to the World Health Organization (WHO)Trusted Source, obesity worldwide has nearly tripled since 1975.

Alongside this trend, there has been an explosion in the sales of lightly regulated, under-researched herbal and dietary weight loss supplements.

About 15%Trusted Source of people in the United States have tried one of these dietary aids, the products of an industry valued at $140 billion in 2020.

The first global review in 19 years regarding the efficacy of herbal and dietary supplements for weight loss was recently presented by researchers from the University of Sydney (USYD) in Australia to the European Congress on Obesity (ECO).

The research, which encompassed two literature reviews including 121 randomized placebo-controlled trials involving over 10,000 participants with overweight or obesity, found insufficient evidence that herbal and dietary supplements produce clinically significant weight loss.

“Our rigorous assessment of the best available evidence finds that there is insufficient evidence to recommend these supplements for weight loss.

Even though most supplements appear safe for short-term consumption, they are not going to provide weight loss that is clinically meaningful.”

At issue are a range of pills, powders, and liquids marketed with the promise that they can help people lose weight.

The products may include entire plants or products in which a plant is an active ingredient.

They may also contain isolates from animal- and plant-based substances, such as fats, fiber, and protein.

“Over-the-counter herbal and dietary supplements promoted for weight loss are increasingly popular, but unlike pharmaceutical drugs, clinical evidence for their safety and effectiveness is not required before they hit the market,” said Bessell.

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